New Approaches in Cardio & Vascular Protection: Dual Renin-Angiotensin System Blockade

Tuesday 4th September 2007

New Approaches in Cardio & Vascular Protection: Dual Renin-Angiotensin System Blockade

Vienna, Austria

It is well established that angiotensin II (a key mediator of the renin angiotensin system [RAS]) is linked to the development of both acute cardiovascular events and chronic cardiovascular damage and disease. Previous studies in heart failure have shown that the addition of an angiotensin receptor blocker (ARB) to standard background therapy can improve cardiovascular endpoints, including death. It is possible that dual RAS blockade may be of particular benefit to a high-risk population, including those patients with multiple risk factors. The landmark ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET^TM) Programme, which has enrolled more than 31,000 patients with a broad range of cardiovascular diseases, will provide the opportunity to establish the benefits of dual protection using telmisartan and ramipril in a high-risk population.

Faculty

Symposium Chairmen

• Salim Yusuf - Population Health Research Institutee McMaster University, Hamilton, Canada
• Björn Dahlöf - Department of Medicine Sahlgrenska University Hospital, Gothenburg, Sweden

Speakers

• Salim Yusuf - Population Health Research Institutee McMaster University, Hamilton, Canada
• Thomas Unger - Institute of Pharmacology and Toxicology Charitè - University Medicine Berlin, Berlin, Germany
• Björn Dahlöf - Department of Medicine Sahlgrenska University Hospital, Gothenburg, Sweden
• Michael Weber - Office of Scientific Affairs SUNY Downstate College of Medicine, New York, USA

Agenda

• Welcome - Björn Dahlöf, Sweden
• Cardiovascular protection: which individuals should be targeted? - Salim Yusuf, Canada
• New concepts of renin angiontensin system blockade - Thomas Unger, Germany
• Clinical effects of renin angiotensin system blockade - Björn Dahlöf, Sweden
• Dual renin angiotensin system blockade: existing and ongoing studies - Michael Weber, USA
• Interactive keypads and panel discussion - Salim Yusuf, Canada

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